USE OF METHODS OF MATHEMATIC STATISTICS FOR PROCESSING OF MEDICAL-BIOLOGICAL DATA FOR REVELATION OF THE ROLE OF CHEMICAL ELEMENTS IN ETHIOPATHOGENESIS OF HUMAN DISEASES

Anatolij Prykhodchenko, Yulia Ulianovskа, Vladislav Ulianoskiy

Abstract


Aim of paper was to appraise the possibility of use of the traditional mathematical statistics methods for biomedical data to processing for determining the role of aluminium, chrome, niobium and lead in functioning of human blood-forming system. An effect of the abovementioned microelements on immunocompetent and blast cells was examined.

Methods. To solve the indicated purposes, it were examined the venous blood leukoconcentrate in 48 of the examined persons. The standard methods of statistics were applied to the obtained data, namely the construction of spreading plot, elements of correlation and regression analysis.

Results. It was obtained, that the reaction of immunocompetent and blast cells is ambivalent and depends upon the level of micronutrient status in human organism. Micronutrient biogenic effect is observed upon its low concentration in blood. An abiogenic effect arises upon the high level of micronutrient status in biological media of human.

Conclusions. Notwithstanding the obtained results, the generally accepted approaches haven’t provided the possibility to determine the faithful character of immunocompetent and blast cells reaction on the level of micronutrient status in human organism and require the elaboration and development of the new approaches considering the revealed nonlinear relation. 


Keywords


hematopoietic system; leukoconcentrate venous blood; correlation analysis; regression analysis

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DOI: http://dx.doi.org/10.21303/2504-5679.2016.00132

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