LEFT VENTRICULAR HYPERTROPHY AND LEFT ATRIAL DILATATION AS MARKERS OF MALIGNANT ARRHYTHMIAS DEVELOPMENT

Abstract

One of the pressing problems of modern cardiology is the study of the etiological and risk factors for sudden cardiac death (SCD). Arrhythmias, which in most cases correlate with signs of myocardial hypertrophy, are important for its occurrence. The most common cause of left ventricular hypertrophy (LVH) is hypertension. However, an equally important trigger mechanism for malignant arrhythmias is coronary heart disease (CHD). It is known that LVH is considered as an independent risk factor for cardiovascular complications.

Methods. The study design included an assessment of the effect of cardiac remodelling, the degree of LVH, and the degree of dilatation of left atrium (LA) on the development of malignant disorders of rhythm and conduction of the heart (DRCH). 78 patients with II degree of hypertension were examined. Patients were divided into two groups depending on the presence of CHD. In each group, there were malignant rhythm and conduction disorders. The control group consisted of 20 healthy people.

Results and discussion. The stages of LVH were equally represented in both groups, but the concentric LVH, the initial degree of LVH, and the dilatation of LA predominated. In patients with malignant DRCH, a moderate degree of LVH predominated. Significantly, more likely malignant DRCH occurred in the second group and presented with high-grade ventricular extrasystoles, prolonged QT interval, and sinus node weakness syndrome.