RESEARCH OF ANTIBACTERIAL PROPERTIES OF THE SURFACE OF THE TITANIUM ALLOYS VT5-1 AND VT6 CONVERTED TO ANATASE TO PREVENT BACTERIAL ADHESION

Oleksandr Samoilenko

Abstract


Aim: to evaluate the effectiveness of preventing the formation of microbial biofilms on the surfaces of implants made of titanium alloys VT5-1, VT6 with a transformed surface into anatase.

Materials and methods. The study was carried out in the bacteriological laboratory of the Severodonetsk multidisciplinary city hospital from January 2019 to September 2019. The ability to prevent the formation of microbial biofilms of Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa was evaluated. The static cell adhesion method and the disco diffuse method were used. The surface of the plates was examined on a XS 6220 UCMJS05100KPA microscope. The intensity of the formation of microbial biofilms on the plates was evaluated visually by the four-cross system.

Results. On all coatings with anatase, in comparison with unmodified plates, the intensity of initial adhesion and the number of bacteria fixed on the surface of the colonies markedly decreased. On surfaces with silica crystals, biofilm formation was minimal. The altered surface of titanium alloys VT5-1 and VT6 anatase and anatase with silicon dioxide crystals does not inhibit microflora growth.

Conclusions. The transformed surface of titanium implants into anatase and anatase with silicon dioxide crystals prevents the fixation of biofilms of microbial associations.


Keywords


antimicrobial coatings; titanium implant; anatase

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References


Haiko, H. V. et. al. (2019). Dvoetapne likuvannia peryproteznoi infektsii kulshovoho suhloba. Zbirnyk naukovykh prats XVIII zizdu ortopediv-travmatolohiv Ukrainy. Ivano-Frankivsk, 239–240.

Berezka, M., Lapshyn, D. (2019). The role of intraoperative microbiology examination in case of infectious complication prevention after the arthroplasty. Zbirnyk naukovykh prats XVIII zizdu ortopediv-travmatolohiv Ukrainy. Ivano-Frankivsk, 236–237.

Costerton, W., Veeh, R., Shirtliff, M., Pasmore, M., Post, C., Ehrlich, G. (2003). The application of biofilm science to the study and control of chronic bacterial infections. Journal of Clinical Investigation, 112 (10), 1466–1477. doi: http://doi.org/10.1172/jci20365

Kalmantaev, T. A., Sadikova, G. T., Perelygin, V. V., Pokhilenko, V. D. (2011). Poluchenie i ocenka effektivnosti antimikrobnykh polimernykh pokrytii na osnove baktericidnykh veschestv BACILLUS CIRCULANS i PAENIBACILLUS POLYMYXA. Mikrobiologiia, 12, 1478–1486.

Shtilman, M. N. (2006). Polimery mediko-biologicheskogo naznacheniia. Moscow: IKC «Akadem-kniga», 400.

Mostovaia, O. S. (2012). Ispolzovanie dentalnykh implantov s modificirovannym biokompozicionnym antimikrobnym pokrytiem (eksperimentalno-klinicheskie issledovaniia). Saratov, 18.

Knetsch, M. L. W., Koole, L. H. (2011). New Strategies in the Development of Antimicrobial Coatings: The Example of Increasing Usage of Silver and Silver Nanoparticles. Polymers, 3 (1), 340–366. doi: http://doi.org/10.3390/polym3010340

Liasnikova, A. V., Lepilin, A. V., Liasnikov, V. N., Smirnov, D. A. Mostovaia, O. S. (2010). Kompleksnoe issledovanie fiziko-khimicheskikh i mediko-biologicheskikh antimikrobnykh svoistv biokompozicionnykh pokrytii dentalnykh implantov. Novye materialnye tekhnologii. Vestnik SGTU, 1 (44), 83–91.

Vakhitov, B. I., Sitdikova, I. D. (2016). Sravnitelnii analiz svoistv pokrytii na titane i ego splavakh, poluchennykh razlichnymi metodami. Lechenie artrozov. Vse, krome zameny sustava. Kazan: Izd-vo Kazan.un-ta, 41–43.

Fishman, M., Kniazhanskaia, M., Nemec, A., Cun, A. (2017). Snizhenie riska tromboza i restenoza pri ispolzovanii stentov s elektretnym otricatelno zariazhennym pokrytiem. Almanakh klinicheskoi mediciny, 45 (3), 234–241.

Bratskaia, S. Iu. (2009). Polisloinye i kovalentno privitye funkcionalnye pokrytiia na osnove polisakharidov dlia predotvrascheniia bakterialnoi adgezii. Vestnik DVO RAN, 2, 84–92.

Vyrva, O. Ye., Shevchenko, I. V., Korolov, O. O. (2019). Artykuliuiuchi speisery kulshovoho suhloba v likuvanni pery proteznoi infektsii. Zbirnyk naukovykh prats XVIII zizdu ortopediv-travmatolohiv Ukrainy. Ivano-Frankivsk, 237–238.




DOI: http://dx.doi.org/10.21303/2585-663.2019.001097

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ISSN 2585-6634 (Online), ISSN 2585-6626 (Print)