Vitaliy Syvolap, Svitlana Zhemanyuk


Ambulatory blood pressure monitoring (ABPM) is a modern method of BP investigation. However, only some ABPM parameters, as diurnal systolic BP (SBP) and diastolic BP (DBP), are used now as the diagnostic guide according to international recommendations. It is pure knowledge in clinical practice about usage and calculation of mean blood pressure (MBP). Such parameter is the steady flow of blood through the aorta and its arteries and equals the cardiac output multiplied by vascular resistance [1], according to some clinical studies may have predictable value as SBP or DBP, however there is no clinical evidence about these parameters, as information how to calculate in ABPM.

The aim of the study is to compare the mean blood pressure calculated by two methods using ABPM parameters.

We selected 20 ambulatory blood pressure monitoring (ABPM) patients (median of age 60 [56; 64] years, 65 % women). ABPM was recorded using a bifunctional device (Incart, S.-P., RF). We calculated MBP as [[(2×DBP)+SBP]/3] [2] and as [DBP+[0.01×exp(4,14-40,74/HR)] ×PP] [3], Formula 1 and Formula 2, respectively. The analysis of difference between results of MBP measurements calculated by two methods was performed using the Bland and Altman method. The data show, that MBP calculated by Formula 1 and Formula 2 are as 87.7 [83.2−90.5] and 91.1 [85.4−93.5] mm Hg, respectively. The limits of agreements for the MBP were 0,49/5,91.

In general, based on the findings of the current study, the measurements of MBP calculated using different formulas show good agreement. Further studies need to have more clinical evidence to analyze the result


ambulatory blood pressure monitoring; ABMP; Blant-Altman plot; blood pressure; BP; mean blood pressure; MBP

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Safar, M. E. (1989). Pulse pressure in essential hypertension: clinical and therapeutical implications. Journal of Hypertension, 7 (10), 769–776. doi: 10.1097/00004872-198910000-00001

Ruoff, B. E., Katz, E. D. (2010). Commonly Used Formulas and Calculations. Clinical Procedures in Emergency Medicine. Amsterdam: Elsevier Mosby Publishing, 1333–1343. doi: 10.1016/b978-1-4160-3623-4.00072-9

Moran, D., Epstein, Y., Keren, G., Laor, A., Sherez, J., Shapiro, Y. (1995). Calculation of Mean Arterial Pressure During Exercise as a Function of Heart Rate. Applied Human Science, 14 (6), 293–295. doi: 10.2114/ahs.14.293

Mancia, G., Fagard, R., Narkiewicz, K., Redon, J., Zanchetti, A., Bohm, M. et. al. (2013). 2013 ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). Journal of Hypertension, 31 (7), 1281–1357. doi: 10.1097/

Kovalenko, V. M. (Ed.) (2016). Sertsevo-sudinni zakhvoriuvannia. Klasifikatsiia, standarty diagnostiki ta likuvannia [Cardiovascular diseases. Classification, practical protocols of diagnosis and treatment]. Ukrainian association of cardiology. Kyiv: Morion, 189.

Safar, M. E. (2000). Pulse pressure, arterial stiffness, and cardiovascular risk. Current Opinion in Cardiology, 15 (4), 258–263. doi: 10.1097/00001573-200007000-00009

Sesso, H. D., Stampfer, M. J., Rosner, B., Hennekens, C. H., Gaziano, J. M., Manson, J. E., Glynn, R. J. (2000). Systolic and Diastolic Blood Pressure, Pulse Pressure, and Mean Arterial Pressure as Predictors of Cardiovascular Disease Risk in Men. Hypertension, 36 (5), 801–807. doi: 10.1161/01.hyp.36.5.801

Benjamin, E. J., Blaha, M. J., Chiuve, S. E., Cushman, M., Das, S. R., Deo, R. et. al. (2017). Heart Disease and Stroke Statistics–2017 Update: A Report From the American Heart Association. Circulation, 135 (10), e146–e603. doi: 10.1161/cir.0000000000000485

Bland, J. M., Altman, D. G. (1999). Measuring agreement in method comparison studies. Statistical Methods in Medical Research, 8 (2), 135–160. doi: 10.1177/096228029900800204

Yoshitomi, Y., Nagakura, C., Miyauchi, A. (2005). Significance of Mean Blood Pressure for Blood Pressure Control. International Heart Journal, 46 (4), 691–699. doi: 10.1536/ihj.46.691

White, W. B. (Ed.) (2016). Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics. Cham: Humana Press, 418. doi: 10.1007/978-3-319-22771-9

Babaei Jandaghi, A., Shakiba, M., Nasseh, H., Korouji, Y., Esmaeili, S., Khadem Maboudi, A. A., Khorshidi, A. (2015). Application of Bland-Altman Method in Comparing Transrectal and Transabdominal Ultrasonography for Estimating Prostate Volume. Iranian Journal of Medical Sciences, 40 (1), 34–39.

Giavarina, D. (2015). Understanding Bland Altman analysis. Biochemia Medica, 25 (2), 141–151. doi: 10.11613/bm.2015.015



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