Pavlo Stavnichenko, Olesya Novohatska


In the overall structure of occupational diseases the large proportion is acute pesticide poisoning (mainly group cases). In recent decades in the structure of agricultural workers’ occupational diseases chemicals poisoning was 14,7-43,5 %.

That is why the purpose of the work was to predict the possibility of acute toxic effects on agricultural workers when working with combined formulations.

Methods. In order to assess the effects of the aforementioned substances on the workers’ organism the coefficient of possible inhalation poisoning (CIPP), the coefficient of pesticide effect selectivity at inhalation effect (CPESinhal.) and at dermal application (CPESderm.) were used.

Results. According to the "Hygienic Classification of Pesticides by Degree of Danger", all studied compounds, as well as combined preparations based on them, are pertained to 4th hazard according to this criterion (CIPP <0,5). Calculated CPESinhal. (103,4-4701,2) and CPESderm. (237,4-12345,7) values for all investigated a.i. were more than 100, which indicates a rather high selectivity of their action.

Discussion. Thus, the obtained results allow to predict the possible negative influence of pesticides of different classes on the initial stages of registration tests of pesticide formulations containing studied active substances

Conclusion. The importance of observance of the established regulations for formulations application (norms and rates of application) and the obligatory use of the recommended individual protecting means for the respiratory and skin protection by agricultural workers during the application of studied pesticides are shown


acute poisoning; risks; coefficient of pesticide effect selectivity; dermal and inhalation effects; coefficient of inhalation poisoning possibility

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Official Site of Social Insurance Fund from industrial accidents and occupational diseases Ukraine (2017). Avaliable at:

Gornostay, O. B. (2013). The development of occupational diseases in Ukraine. Naukoviy vіsnik NLTU Ukraini, 23 (16), 396–401.

Kharchenko, O. A., Babich, V. A. (2011). Acute pesticide poisoning in the structure of occupational morbidity in agricultural workers. Suchasnі problemi toksikologіi, 5, 150–151.

Balan, G. M., Bubalo, N. M. (2013). Reasons, structure and clinical symptoms of acute poisoning by pesticides in agricultural workers in terms of its reform. Suchasnі problemi toksikologіi, kharchovoi ta khіmіchnoi bezpeki, 4, 22–29.

Sokolova, M. P. (2009). Problems of identification and registration of occupational diseases in Ukraine. Kyiv, 20.

Stavnichenko, P. V., Antonenko, A. M., Korshun, M. M., Bardov, V. H. (2016). Toxicological and hygienic regulation and hazard evaluation of a new fungicide – cyflufenamide. Medichnі perspektivi, XXI (2), 106–111.

Storchous, I. (2015). Ecology and pesticides. Ahrobiznes sohodni, 1-2. Avaliable at:

Sergeev, S. G., Chayka, Yu. G. (2008). Assessment of the possibility of acute toxic effects when working with pesticides, taking into account their selectivity of action. Suchasni problemy toksykolohiyi, 4, 29–31.

Hygienic classification of pesticides according to the degree of danger: DSanPiN (1998). Kyiv: Ministry of health of Ukraine, 20.

Vavrinevych, O. P. (2014). Comparative toxicological and hygienic assessment of the risk of development of acute inhalation poisoning of professional contingents by fungicides of different classes (review of literature and results of own research). Ukrainskyi zhurnal z problem medytsyny pratsi, 3 (40), 83–90.



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ISSN 2585-6634 (Online), ISSN 2585-6626 (Print)